Node 2, the United States On-orbit Segment (USOS), is home to four Crew Quarters (CQs) designed as sleeping quarters for crew members during their time in orbit. Each CQ provides a personal, private space for crew members to sleep, relax, and connect with home during their stay on the ISS. The CQ is equipped with an individual ventilation system, acoustical mitigation materials, laptop connections, and internet access, allowing crew members to communicate with family and friends.

Since their deployment in 2008, CQ performance has been closely monitored to ensure that the design continues to meet requirements. Over the past four years, minor issues have been discovered due to on-orbit environments, and modifications have been made to the existing CQ outfitting to enhance crew safety and comfort.

Sleeping in weightlessness is complicated; to avoid floating while sleeping, astronauts use sleeping bags that are attached to the CQ.